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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GRM2 All Species: 42.42
Human Site: S173 Identified Species: 77.78
UniProt: Q14416 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14416 NP_000830.2 872 95568 S173 A S T S A K L S D K S R Y D Y
Chimpanzee Pan troglodytes A3QNZ8 839 95029 V136 S N Y I S R V V A V I G P D N
Rhesus Macaque Macaca mulatta A3QP01 839 95041 V136 S N Y V P R V V A V I G P D N
Dog Lupus familis XP_541867 872 95696 S173 A S T S A K L S D K S R Y D Y
Cat Felis silvestris
Mouse Mus musculus Q14BI2 872 95869 S173 A S T S A K L S D K S R Y D Y
Rat Rattus norvegicus P31421 872 95755 S173 A S T S A K L S D K S R Y D Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518731 870 95758 S173 A S T S A K L S D K S R Y D Y
Chicken Gallus gallus XP_416842 879 98936 S179 A S T S A K L S D K S R Y D Y
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q5U9X3 867 97118 S178 A S T A T I L S D K S R F P A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P91685 976 108467 S186 A S T A K T L S D K T R F D L
Honey Bee Apis mellifera NP_001011624 933 103448 S197 A S T A K A L S D K T R F D Y
Nematode Worm Caenorhab. elegans Q09630 999 113258 S230 A S T N A D L S D K N R F E Y
Sea Urchin Strong. purpuratus XP_784936 1474 165598 S747 A S T S A R L S D K S R F E F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 27.6 27.6 98.1 N.A. 97.4 97.8 N.A. 88.3 67.9 N.A. 25.5 N.A. 45.7 47 39.9 32.2
Protein Similarity: 100 46.3 46.3 98.9 N.A. 98.5 98.7 N.A. 92.7 82.2 N.A. 43.8 N.A. 61.7 63.3 55.6 43.4
P-Site Identity: 100 6.6 6.6 100 N.A. 100 100 N.A. 100 100 N.A. 60 N.A. 60 66.6 66.6 73.3
P-Site Similarity: 100 40 33.3 100 N.A. 100 100 N.A. 100 100 N.A. 73.3 N.A. 80 86.6 93.3 100
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 85 0 0 24 62 8 0 0 16 0 0 0 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 8 0 0 85 0 0 0 0 77 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 16 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 39 0 8 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 16 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 8 0 8 0 0 0 0 16 0 0 0 0 % I
% Lys: 0 0 0 0 16 47 0 0 0 85 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 85 0 0 0 0 0 0 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 16 0 8 0 0 0 0 0 0 8 0 0 0 16 % N
% Pro: 0 0 0 0 8 0 0 0 0 0 0 0 16 8 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 24 0 0 0 0 0 85 0 0 0 % R
% Ser: 16 85 0 54 8 0 0 85 0 0 62 0 0 0 0 % S
% Thr: 0 0 85 0 8 8 0 0 0 0 16 0 0 0 0 % T
% Val: 0 0 0 8 0 0 16 16 0 16 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 16 0 0 0 0 0 0 0 0 0 47 0 62 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _